SPIRIVA RESPIMAT (tiotropium bromide) Inhalation Spray is a 2 puffs, 1 time daily, inhaled prescription maintenance medication that has been clinically proven to significantly improve lung function. It works by opening airways to help people with COPD (Chronic Obstructive Pulmonary Disease) breathe better—for a full 24 hours.

SPIRIVA RESPIMAT is not for sudden COPD symptoms. Always carry a rescue inhaler.

Learn about SPIRIVA RESPIMAT

Delivers a soft mist that helps ease the effort* to inhale the medicine

  • Is steroid free

  • Helps keep airways open for a full 24 hours

SPIRIVA RESPIMAT is not for sudden COPD symptoms. Always carry a rescue inhaler.

Learn about what to expect from SPIRIVA RESPIMAT

* As with all inhaled medicines, the actual amount of medicine that is delivered to the lung may vary depending on correct use of the inhaler and the patient's ability to breathe in through the inhaler for at least 1.5 seconds.

While rescue inhalers treat sudden symptoms, maintenance treatments, like SPIRIVA RESPIMAT, are medicines you take daily to manage your COPD symptoms.

Learn about rescue and maintenance treatments

Yes. You should continue taking oxygen for your COPD as prescribed, unless your doctor tells you otherwise.

COPD is a common, preventable, and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation. It can make it difficult to get air out of your lungs and new air back in. While there is no cure for COPD, with lifestyle changes and medication, you may be able to breathe better and manage your symptoms.

Learn more about COPD

Some symptoms of COPD include:

  • Shortness of breath

  • Coughing

  • Chest tightness

  • Wheezing

Learn more about treating COPD

Stopping smoking is one of the most important things you can do to slow the progression of COPD. SPIRIVA RESPIMAT can help you breathe easier, even if you have smoked. One time daily SPIRIVA RESPIMAT is proven to help people who smoked a pack a day for 10 years breathe better.

Ask your doctor if SPIRIVA RESPIMAT is right for you

Many things can cause COPD symptoms to suddenly worsen. Triggers include:

  • Cigarette smoke and smoking

  • Extreme hot or cold weather

  • Air pollution

COPD is a disease that can get worse over time, which means that symptoms can turn into something called a flare-up or exacerbation. It’s important to know what can cause a flare-up and what you can do to guard against them. SPIRIVA RESPIMAT has been shown to help significantly reduce the risk of flare-ups.

What can cause a flare-up?

Most flare-ups are caused by a lung infection like the common cold, so germs are a threat. Other causes, called triggers, can irritate your lungs and cause flare-ups. Here are some of the most common triggers that should be avoided:

  • Weather that is very hot, very cold, or very humid

  • Pollution outside from smog and ozone, or inside from tobacco smoke and wood-burning fires

  • Household cleaning products with bleach or ammonia

  • Allergies to dust, animals, or pets

Yes! Ask your doctor about ways to help you breathe more efficiently during the day. He or she can also recommend relaxation techniques to use when you’re short of breath.

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In many cases, yes. In fact, exercise can have many benefits for a COPD sufferer. Some low-impact exercise, such as walking, stretching, and gentle strengthening exercises, can help decrease shortness of breath and improve your overall level of energy. Talk to your doctor before starting any new activities. Even with COPD, it may be possible and helpful to find an exercise program that works for you.

There’s a lot you can do to keep COPD under control. For instance:

  • Avoid triggers, such as dust or smoke, that can irritate your lungs

  • Get vaccinated against the flu and pneumonia

  • Avoid germs during cold and flu season

  • Get your family on board with encouragement and support

  • Take all medicines as recommended by your doctor

INDICATIONS

SPIRIVA RESPIMAT, 2.5 mcg, is a long-term, once-daily, prescription medicine used to control symptoms of chronic obstructive pulmonary disease (COPD) by relaxing your airways and keeping them open. COPD includes chronic bronchitis and emphysema. SPIRIVA RESPIMAT also reduces the likelihood of COPD flare-ups (COPD exacerbations).

SPIRIVA RESPIMAT, 1.25 mcg, is a long-term, once-daily, prescription maintenance treatment of asthma for people 6 years and older.

SPIRIVA RESPIMAT is not a treatment for sudden symptoms of asthma or COPD.

IMPORTANT SAFETY INFORMATION

Do not use SPIRIVA RESPIMAT if you are allergic to tiotropium, ipratropium, atropine or similar drugs, or any ingredient in these medicines.

SPIRIVA RESPIMAT is not a rescue medicine and should not be used for treating sudden breathing problems. Your doctor may give you other medicine to use for sudden breathing problems.

SPIRIVA RESPIMAT can cause allergic reactions. Symptoms can include raised red patches on your skin (hives), itching, rash and/or swelling of the lips, tongue, or throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking the medicine and get immediate medical care.

SPIRIVA RESPIMAT can cause your breathing to suddenly get worse (bronchospasm). If this happens, use your rescue inhaler, stop taking SPIRIVA RESPIMAT, and call your doctor right away or seek emergency medical care.

SPIRIVA RESPIMAT can increase the pressure in your eyes (acute narrow-angle glaucoma), which can cause the following symptoms: eye pain, blurred vision, seeing halos or colored images along with red eyes. If you have any of these symptoms, stop taking your medicine and call your doctor right away.

Dizziness and blurred vision may occur with SPIRIVA RESPIMAT. If you experience these symptoms, use caution when engaging in activities such as driving a car, or operating appliances or other machines.

SPIRIVA RESPIMAT can cause new or worsened urinary retention. Symptoms of blockage in your bladder and/or enlarged prostate may include difficulty passing urine and/or painful urination. If you have any of these symptoms, stop taking your medicine and call your doctor right away.

The most common side effects reported with SPIRIVA RESPIMAT in patients with COPD include sore throat, cough, dry mouth, and sinus infection.

The most common side effects with SPIRIVA RESPIMAT in adult patients with asthma were sore throat, headache, bronchitis, and sinus infection. The side effect profile for adolescent and pediatric patients was comparable to that observed in adult patients with asthma.

Do not spray SPIRIVA RESPIMAT into your eyes, as this may cause blurring of vision and pupil dilation.

Tell your doctor all the medicines you take, including eye drops. Ask your doctor if you are taking any anticholinergic medicines because taking them together with SPIRIVA RESPIMAT can increase side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

CL-SVR-100067 2.15.2017

Please see full Prescribing Information, including Instructions for Use, for SPIRIVA RESPIMAT.