COPD, or Chronic Obstructive Pulmonary Disease, is the term used to describe lung and airway diseases that restrict breathing.

In COPD there is irreversible damage to the lungs and airway that makes it hard to breathe. If you have been diagnosed with emphysema or chronic bronchitis, this means you have COPD.

Some of the changes in your lungs and airways due to COPD can include:

  • Loss of elasticity in the airways and air sacs of your lungs
  • Inflammation and/or scarring (fibrosis) and narrowing of the airways
  • Thick mucus in your airways
  • Damage to the walls between the air sacs in your lungs

What are the types of COPD?

Two types of COPD are emphysema and chronic bronchitis. People with COPD often have features and symptoms of both.

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Emphysema

Involves damaged and enlarged alveoli (air sacs). The most common symptom is shortness of breath, also known as dyspnea.

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Chronic bronchitis

Is inflammation in the large airways, which narrows them and makes a lot of mucus. The most common symptom is cough.

Understanding COPD

Explore an interactive 3D journey inside the lungs to see how breathing works in real time.

Take a virtual tour to understand how COPD impacts lung function and overall respiratory health.

What are the symptoms of COPD?

Symptoms of COPD can include:

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Cough with mucus that won’t go away after three months or longer

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Difficulty taking a deep breath

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Shortness of breath even with mild exertion or daily activity

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Wheezing and other lung sounds

What are COPD flare-ups?

People with COPD often get flare-ups, also known as exacerbations, which are worsening symptoms. These can include severe difficulty breathing, thicker mucus, wheezing, and cough. Severe exacerbations can require hospitalization.

As COPD gets progressively worse over time, flare-ups can become more severe and happen more often. Progression usually occurs over the course of years. However, for some patients COPD can worsen more quickly.

What causes COPD?

The most common cause of COPD is damage to the lungs from smoking. Other causes may include:

  • Alpha-1 antitrypsin deficiency (“alpha-1) which is a genetic disorder that can cause lung damage
  • Secondhand smoke
  • Environmental factors such as toxins in the air
  • Occupational factors such as dust and fumes at your job

How is COPD managed and treated?

There is no cure for COPD. Treatment focuses on improving symptoms and reducing the risk of flare-ups. You will work with your health care team to come up with a treatment plan that best meets your needs.

Some recommendations your doctor may have include:

Quitting Smoking

Quitting smoking

The best way to slow down the progression of COPD is to quit smoking now.

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Inhaled medicines

Such as bronchodilators and steroids can reduce the inflammation in your airways to health you breathe.

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Oxygen therapy

May be required to improve oxygen levels

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Pulmonary rehabilitation

Is a program that involves exercise and education that can improve your lung strength and help you manage your COPD

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Corticosteroids

Can help to reduce inflammation during exacerbations

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Positive airway pressure

Such as BiPAP machine can help you to breathe, especially during an exacerbation

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Lung volume reduction (LVR)

May be suggested if you have severe COPD and if you’re a good candidate. This involves surgery or a procedure that reduces trapped air in the lungs

Please see the FAQs for answers to more questions about COPD.

INDICATIONS

SPIRIVA RESPIMAT, 2.5 mcg, is a long-term, once-daily, prescription medicine used to control symptoms of chronic obstructive pulmonary disease (COPD) by relaxing your airways and keeping them open. COPD includes chronic bronchitis and emphysema. SPIRIVA RESPIMAT also reduces the likelihood of COPD flare-ups (COPD exacerbations).

SPIRIVA RESPIMAT, 1.25 mcg, is a long-term, once-daily, prescription maintenance treatment of asthma for people 6 years and older.

SPIRIVA RESPIMAT is not a treatment for sudden symptoms of asthma or COPD.

IMPORTANT SAFETY INFORMATION

Do not use SPIRIVA RESPIMAT if you are allergic to tiotropium, ipratropium, atropine or similar drugs, or any ingredient in these medicines.

SPIRIVA RESPIMAT is not a rescue medicine and should not be used for treating sudden breathing problems. Your doctor may give you other medicine to use for sudden breathing problems.

SPIRIVA RESPIMAT can cause allergic reactions. Symptoms can include raised red patches on your skin (hives), itching, rash and/or swelling of the lips, tongue, or throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking the medicine and get immediate medical care.

SPIRIVA RESPIMAT can cause your breathing to suddenly get worse (bronchospasm). If this happens, use your rescue inhaler, stop taking SPIRIVA RESPIMAT, and call your doctor right away or seek emergency medical care.

SPIRIVA RESPIMAT can increase the pressure in your eyes (acute narrow-angle glaucoma), which can cause the following symptoms: eye pain, blurred vision, seeing halos or colored images along with red eyes. If you have any of these symptoms, stop taking your medicine and call your doctor right away.

Dizziness and blurred vision may occur with SPIRIVA RESPIMAT. If you experience these symptoms, use caution when engaging in activities such as driving a car, or operating appliances or other machines.

SPIRIVA RESPIMAT can cause new or worsened urinary retention. Symptoms of blockage in your bladder and/or enlarged prostate may include difficulty passing urine and/or painful urination. If you have any of these symptoms, stop taking your medicine and call your doctor right away.

The most common side effects reported with SPIRIVA RESPIMAT in patients with COPD include sore throat, cough, dry mouth, and sinus infection.

The most common side effects with SPIRIVA RESPIMAT in adult patients with asthma were sore throat, headache, bronchitis, and sinus infection. The side effect profile for adolescent and pediatric patients was comparable to that observed in adult patients with asthma.

Do not spray SPIRIVA RESPIMAT into your eyes, as this may cause blurring of vision and pupil dilation.

Tell your doctor all the medicines you take, including eye drops. Ask your doctor if you are taking any anticholinergic medicines because taking them together with SPIRIVA RESPIMAT can increase side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

CL-SVR-100067 2.15.2017

Please see full Prescribing Information, including Instructions for Use, for SPIRIVA RESPIMAT.